According to European Union Regulation 1223/2009 for cosmetics products, which entered into force on July 11, 2013, it is requested to establish a product safety assessment report for the products currently on the market or newly introduced to the market. Safety Assessment of a cosmetic product is a part of Cosmetic Product Safety Report and should prove that the chemical components of the cosmetic product and the product itself is safe for human health.
Margin of Safety (MoS) of product components must be calculated in the product safety assessment report. The highest application amount (No observed adverse effect level - NOAEL) of the substance for which no adverse effect is observed, is used in MoS calculations. Furthermore, in order to be able to evaluate all toxicological routes of absorption and systematic effects, the amount of expected blood cross-over of the component, ie Systematic Exposure Dose (SED), is also required.
MS Star's experienced and professional team is ready to serve you to prepare the Safety Assessment of your product.